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Darmstadt 98: Paik vor Absprung – „Wechsel ist in den letzten Zügen

Darmstadt 98: Paik vor Absprung – „Wechsel ist in den letzten Zügen
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EMA expects Johnson & Johnson to file for vaccine approval within days

EMA expects Johnson & Johnson to file for vaccine approval within days New BioNTech production site will have capacity to produce 750m doses annually Fri, Feb 12, 2021, 17:04 Updated: Fri, Feb 12, 2021, 21:26 The first stage of BioNTech’s vaccine process, producing the active ingredient known as mRNA, has begun at a new plant in Marburg. Photograph: AFP via Getty   The European Medicines Agency (EMA) expects Johnson & Johnson to file for approval of its Covid-19vaccine in the EU within the next few days. Approval of this inoculation is viewed by many as pivotal in speeding up the overall rollout of vaccines, in part because it may only require one dose.

Merck KGaA, Darmstadt, Germany Announces Update on the INTR@PID Clinical Program Including Lung 037 Study

Not intended for UK-based media Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced an update on the Phase III [email protected] Lung 037 study and the extensive [email protected] clinical trial program for the potential first-in-class investigational bifunctional immunotherapy bintrafusp alfa, in difficult-to-treat cancers, including biliary tract cancer (BTC) and cervical cancer. The comprehensive [email protected] program is designed to assess the impact of bintrafusp alfa across distinct cancers and settings where TGF-β is thought to play a driving role. TGF-β is a cytokine that is known to be associated with tumor propagation and metastatic potential such as local immunosuppression, fibrosis, growth of tumor blood vessels and chemo- or radiotherapy resistance through several mechanisms. Trapping TGF-β in the tumor microenvironment on top of PD-L1 blockade is thought to be transformative in different clinical settings.

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