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A research pioneer in rare genetic diseases was one of the recipients of the prestigious AMA Award for Government Service. Dan Kastner, MD, PhD, devoted his more than three-decade career to diagnosing and treating rare genetic diseases characterized by fever and inflammation that often result in disabling conditions and death. His work has provided detailed molecular explanations for these illnesses.
Dr. Kastner directs the National Human Genome Research Institute’s division of intramural research and heads the inflammatory disease section. He has seen his work become the conceptual basis for effective targeted therapies. It has informed medicine’s understanding of more common illnesses as well.