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Diagnostic and Interventional Cardiology

Dapagliflozin Did Not Significantly Reduce Organ Failure or Death in High-Risk Hospitalized COVID-19 Patients

Dapagliflozin Did Not Significantly Reduce Organ Failure or Death in High-Risk Hospitalized COVID-19 Patients Phase III DARE-19 trial shows SGLT2 inhibitor is well-tolerated in acutely ill patients Dapagliflozin did not significantly reduce organ failure or death in high-risk hospitalized COVID-19 patients in the DARE-19 trial results, presented at ACC.21. May 18, 2021  Dapagliflozin (Farxiga), a sodium-glucose co-transporter 2 (SGLT2) inhibitor, did not significantly reduce the risk of organ failure or death or improve recovery in patients hospitalized with COVID-19 (SARS-CoV-2) who are at high risk of developing serious complications compared to placebo, according to data presented at the American College of Cardiology (ACC) 2021 Scientific Session. 

DARE-19 Didn t Pay Off for Farxiga in COVID-19

SGLT2 Flops in COVID; Uproar Over J&J Vax Clots; Monoclonal Antibody for STEMI

email article One thing an SGLT2 won t do? Dapagliflozin (Farxiga) flopped for hospitalized COVID-19 patients in the phase III DARE-19 trial. Full results are coming at the American College of Cardiology meeting. ( Pharmaphorum) Johnson & Johnson s COVID vaccine is now the center of attention for rare thrombotic events. (FDA) Post-discharge anticoagulation for COVID-19 patients was associated with 46% lower risk of major thromboembolism or death in one hospital system s registry data. ( Blood) Kaiser Health News. Journal of the American College of Cardiology) Medtronic has a class I recall out on Evera, Viva, Brava, Claria, Amplia, Compia, and Visia ICDs and CRT-Ds due to short circuiting that depletes the battery, sometimes in just 1 day, the FDA cautioned.

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