WASHINGTON Researchers have developed a new technique that allows microscopic fluorescence imaging at four times the depth limit imposed by light diffusion. Fluorescence microscopy is often used to image molecular and cellular details of the.
The way the human brain works remains, to a great extent, a topic of controversy. One reason is our limited ability to study neuronal processes at the level of single cells and capillaries across the entire living brain without employing highly invasive surgical methods. This limitation is now on the brink of change.
New Imaging Technique Helps Visualize Deep Cerebral Microvasculature in Mouse Brain
Written by AZoOpticsMay 28 2021
An innovative technique developed by scientists enables microscopic fluorescence imaging at depth limits that are four times greater than those imposed by light diffusion.
A new imaging method can capture images of vasculature deep in the brains of mice. A conventional widefield fluorescence image of the mouse brain taken non-invasively in the visible light spectrum is shown on the left, while the non-invasive localization-based DOLI approach operating in the NIR-II spectral window is shown on the right. Image Credit: Daniel Razansky, University of Zurich and ETH Zurich.
The way the human brain works remains, to a great extent, a topic of controversy. One reason is our limited ability to study neuronal processes at the level of single cells and capillaries across the entire living brain without employing highly invas
Washington [US], May 28 (ANI): Researchers have developed a new technique that allows microscopic fluorescence imaging at four times the depth limit imposed by light diffusion.