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Genetic modifiers of p53 and their potential in breast cancer therapies
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Exposure to Common Chemical Preservative During Pregnancy May Reduce Protection Against Breast Cancer
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Propylparaben Exposure During Pregnancy Raise the Risk of Breast Cancer by Angela Mohan on March 16, 2021 at 6:36 PM
Exposure to low doses of propylparaben an estrogen-like chemical used as a preservative in personal care products and foods, can modify pregnancy-related changes in the breast in ways that may reduce the normal protection against breast cancer that pregnancy hormones convey, according to a new study being published in the Endocrine Society s journal
Endocrinology.
These results, from an animal study that also will be presented at ENDO 2021, the Endocrine Society s annual meeting, lend evidence that propylparaben is an endocrine-disrupting chemical, the researchers say.
An endocrine-disrupting chemical interferes with the actions of hormones in the body. These chemicals can affect hormone-sensitive organs such as the mammary gland, the milk-producing duct in the breast, said the study s senior author Laura N. Vandenberg of the University of
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WASHINGTON Low doses of propylparaben an estrogen-like chemical used as a preservative in personal care products and foods can alter pregnancy-related changes in the breast in ways that may reduce the normal protection against breast cancer that pregnancy hormones convey, according to a new study being published in the Endocrine Society s journal
Endocrinology.
These results, from an animal study that also will be presented at ENDO 2021, the Endocrine Society s annual meeting, lend evidence that propylparaben is an endocrine-disrupting chemical, the researchers say.
An endocrine-disrupting chemical interferes with the actions of hormones in the body. These chemicals can affect hormone-sensitive organs such as the mammary gland, the milk-producing duct in the breast, said the study s senior author Laura N. Vandenberg of the University of Massachusetts in Amherst, Mass.
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IMAGE: Senior author Laura Vandenberg is an associate professor in the UMass Amherst School of Public Health and Health Sciences. view more
Credit: UMass Amherst
Low doses of propylparaben - a chemical preservative found in food, drugs and cosmetics - can alter pregnancy-related changes in the breast in ways that may lessen the protection against breast cancer that pregnancy hormones normally convey, according to University of Massachusetts Amherst research.
The findings, published March 16 in the journal
Endocrinology, suggest that propylparaben is an endocrine-disrupting chemical that interferes with the actions of hormones, says environmental health scientist Laura Vandenberg, the study s senior author. Endocrine disruptors can affect organs sensitive to hormones, including the mammary gland in the breast that produces milk.
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