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Cosmetic laser may boost effectiveness of certain anti-cancer therapies

 E-Mail BOSTON - Use of a cosmetic laser invented at Massachusetts General Hospital (MGH) may improve the effectiveness of certain anti-tumor therapies and extend their use to more diverse forms of cancer. The strategy was tested and validated in mice, as described in a study published in Immune checkpoint inhibitors are important medications that boost the immune system s response against various cancers, but only certain patients seem to benefit from the drugs. The cancer cells of these patients often have multiple mutations that can be recognized as foreign by the immune system, thereby inducing an inflammatory response. In an attempt to expand the benefits of immune checkpoint inhibitors for additional patients, a team led by David E. Fisher, MD, PhD, director of the Mass General Cancer Center s Melanoma Program and director of MGH s Cutaneous Biology Research Center, conducted experiments in mice with a poorly immunogenic melanoma that is not hindered by immune checkpoint i

Shiseido research finds men s skin is more susceptible to oxidative stress

A new study by Japanese cosmetics firm Shiseido has found that men’s skin is less tolerant to oxidative stress, suggesting it is more delicate and in need of more tailored skin care solutions for male skin. The company undertook this research to clarify how the physiology of skin between men and woman differ fundamentally. Previous research has uncovered that in general, men’s skin has a reduced barrier function and tend to produce more sebum. The firm conducted a survey of men and women in their 20s and 30s and found more characteristic differences such as male skin being more susceptible to UV damage than women.

Age-related macular degeneration could spur better treatments: Study

Age-related macular degeneration could spur better treatments: Study ANI | Updated: Dec 13, 2020 18:13 IST Boston [US], December 13 (ANI): New research reveals insights into potential drivers of the disease which currently has no cure that could be targeted through prevention or treatment strategies. The findings of the study by investigators at Massachusetts General Hospital (MGH) are published in eLife. Two inflammatory pathways involving complement (which is an immune system component) and a protein complex called the inflammasome (which, as its name suggests, triggers inflammation) promote the formation of abnormal blood vessels that are hallmarks of wet AMD, but it s unclear how these pathways are activated.

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