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SGLT2 Inhibitor No Help for ICU Patients With Acute Organ Dysfunction

Secondary findings of trial only suggest a potential benefit in kidney protection

United kingdomLennie pg derdeFernando zampieriIsraelita albert einsteinUniversity of pittsburghUniversity of utrechtHospital israelita albert einsteinCritical care reviews

Liberal Blood Transfusion After Traumatic Brain Injury May Hold Benefit

Trial didn't meet primary outcome, but functional independence scores were better

United kingdomGlasgow cityJudy georgeAlexis turgeonPatient healthNew england journalCritical care reviewsFunctional independence measureBrain injuryGlasgow coma scaleGlasgow outcome scale extendedMedpage todayEngland journalEnglj med

Prolonged Beta-Lactam Dosing Boosts Survival in Sepsis, Septic Shock

Trial and meta-analysis add strength to weak guidelines

New zealandNoord hollandUnited kingdomJasona robertsMichiel van agtmaelW joost wiersingaJoelm dulhuntyUq centre for clinical researchSepsis campaignLactam infusion groupAmsterdam university medical centerRoyal brisbaneCritical care reviewsClinical researchSurviving sepsis campaignBeta lactam infusion group

Amino Acid Infusion Before Cardiac Surgery Reduced Acute Kidney Injury

The amino acid mixture reduced stage 3 AKI by 44% compared with placebo

New yorkUnited statesUnited kingdomGiovanni landoniSan raffaele scientific instituteRaffaele scientific instituteNew england journalCritical care reviewsKidney diseaseImproving global outcomesNew york cityEngland journalEnglj med

Upping CO2 Does Not Benefit OHCA Patients: TAME

Maintaining hypercapnia for the first 24 hours in comatose patients resuscitated after out-of-hospital cardiac arrest did not improve outcomes in a large, randomized trial.

Glasgow cityUnited kingdomNorthern irelandNew zealandAlistair nicholHealth research council of new zealandHealth research board of irelandResearch council of australiaUniversity college dublin school of medicineNational healthUniversity college dublin schoolCritical care reviewsNew england journalGlasgow outcome scaleModified rankin scaleAnalogue scale

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