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Plitidepsin was 27.5-fold more potent against SARS-CoV-2 than remdesivir, a drug that received FDA emergency use authorization in 2020 for the treatment.

New yorkUnited statesSouth africaUniversity collegeNew south walesSouth africanKevan shokatKris whiteNevan kroganClare jollyAdolfo garcUniversity college londonUc san francisco quantitative bioscience instituteNational institute of allergyCoronavirus research consortiumCentre for integrative biological signalling studies