In a systematic review and meta analysis, Tie-Ning Zhang and colleagues investigate the associations between maternal pre-gestational diabetes and gestational diabetes and congenital heart defects and other congenital anomalies in offspring.
Microarray testing in pregnancy is used to detect chromosomal abnormality in the unborn child. It is also useful for individuals who do not fit in a specifically known syndrome such as Down syndrome or other abnormalities such as Developmental delay.
In an observational study, Mikkel Ankarfeldt and colleagues study exposure to the SNRI duloxetine during pregnancy and risk of congenital malformation and stillbirth in offspring, using nationwide data from Denmark and Sweden.