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Use of Povetacicept in Treatment of IgA Nephropathy

Drs Jonathan Barratt and Brad Rovin comment on clinical trial data regarding the use of povetacicept for the treatment of IgAN.

United statesBrad rovinJonathan barrattAmerican society of nephrologyAmerican societyComplement inhibitionB cell modulationBlys april

Dual Inhibition of BlyS and APRIL in IgA Nephropathy

Nephrology experts explore the role of dual inhibition of BlyS and APRIL in the treatment of IgAN, and how this can impact disease pathogenesis.

Jonathan barrattBrad rovinComplement inhibitionB cell modulationBlys april targeting

New Therapies in IgA Nephropathy

Brad Rovin, MD, outlines the use of complement inhibitors as an alternative to systemic glucocorticoids for the treatment of IgAN.

Brad rovinJonathan barrattComplement inhibitionB cell modulationBlys april targeting

The Pathophysiology of IgAN and Use of Immunomodulating Therapies

An expert nephrologist provides an overview of the pathophysiology of IgAN before discussing new immunomodulating therapies in clinical trials.

Chee kay cheungEuropean renal associationVisionary studyPro inflammatory effectMesangial cell activationB cellComplement inhibitionMonoclonal antibodyClinical trialNaiveb cellOrigin trial

Complement therapy in transplant patients in C3G

Anuja Java, MD, discusses the role of complement inhibitors in transplant patients with C3G.

Jonathan barrattKidney transplantComplement inhibitionC3 inhibitor

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