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Studies in Mice Help to Explain Why Redheads Have Different Pain Thresholds
April 6, 2021
Source: Photo by Colton Sturgeon on Unsplash
New research led by investigators at Massachusetts General Hospital (MGH) has offered up new insights into why people with red hair exhibit altered sensitivity to certain kinds of pain. The results of studies in mice with loss of melanocortin 1 receptor (MC1R) function could help point to new ways to manipulate the body’s natural mechanisms for controlling pain perception, for example, by designing new medications that inhibit receptors that are involved in sensing pain.
“Our ongoing work is focused on elucidating how additional skin-derived signals regulate pain and opioid signaling,” said Lajos V. Kemény, MD, PhD, a research fellow in Dermatology at MGH, who is co-senior author of the team’s paper, in