Being late. The days take on a life of their own. So, but i wanted to say good morning. Good morning, dr. Collins, welcome back to labor hhs to the appropriations subcommittee. Let me just say a thank you on behalf of the of the subcommittee for hosting members of the subcommittee for the site visit at the nih campus last week. We had a wonderful opportunity to learn more about nihs work. We met with the researchers who were working to cure Sickle Cell Disease, to develop treatments for major depression, the shrinkage of cancer tumors in children. We heard from participants whose lives have been changed by Clinical Trials. So it was a moving and an informative, but a very moving experience, as well. Let me welcome our witnesses including the five institute and Center Directors who join us today, and in addition, and always a great addition dr. Francis collins who has joined us many times, director of the National Institutes of health. Today joined by dr. Bruce tromberg, by the institut