Its lowest level since july 2012. Russian Prime Minister Dimitry Medvedev says sanctions against russia have damaged International Relations. Speaking exclusively to cnbc, he says moscow has not closed door to anyone, but a reset with the u. S. Is not possible right now. No, of course not. Its absolutely impossible, lets be clear. We did not come up with these sanctions, lets be clear. Announcer youre watching worldwide exchange, bringing you Business News from around the globe. Shares in shire are plunging at the bottom of the ftse after abvie said it would reconsider its takeover. You can see its down 26 . Shire has urged the u. S. Giant to proceed with the deal saying the group could face a 1. 6 billion if it walks away. The news is looking at overtakover targets circled by firms looking to take advantage of stable tax arrangements in the uk. As tra and smith both down 4 . Catherine, a very big move for shire off the back of this. Absolutely. Despite shire insisting that this deal i