Overly stringent RCT exclusion criteria do not appropriately account for the heterogeneity
of vulnerable characteristics observed in real-world populations. Treatment decision
information is scarce for such individuals, which might affect health outcomes. We
discuss the challenges facing the inclusivity of such individuals and highlight the
strength of real-world evidence as an integrative solution in complementing RCTs and
increasing the completeness of evidence-based medicine assessments in evaluating the
effectiveness of treatment decisions.
1.09.2022 - Psoriasis may be underdiagnosed in UK primary care settings, according to research led by researchers from The University of Manchester. The findings, published in The British Journal of General Practice, show that missed opportunities for early diagnosis of the potentially debilitating condition are relatively common in general practice.