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Cancer Immunotherapy Hampered by T Cell Inhibitory Checkpoint VISTA Protein

Cancer Immunotherapy Hampered by T Cell Inhibitory Checkpoint VISTA Protein
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Sheikha fatimaBrian gastmanStefanie avrilTimothy chanLi lily wangCase western reserve universityGlobal centerCleveland clinic centerCleveland clinic ledScience immunologyDia royCleveland clinicPrecision immuno oncologyMubarak endowed chair

Immune checkpoint protein VISTA can directly turn off T-cells during immunotherapy, study finds

A Cleveland Clinic-led team of scientists and physicians have discovered that the immune checkpoint protein VISTA can directly turn off tumor-fighting T-cells during immunotherapy and resist treatment.

Sheikha fatimaLi lily wangKeman zhangTimothy chanBrian gastmanStefanie avrilTyler albanGlobal centerCleveland clinic centerCase western reserve universityCleveland clinic ledScience immunologyCleveland clinicTranslational hematologyPrecision immuno oncologyMubarak endowed chair

Research finds the protein VISTA directly blocks T cells from functioning in immunotherapy

Research finds the protein VISTA directly blocks T cells from functioning in immunotherapy
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Li lily wangTyler albanKeman zhangBrian gastmanTimothy chanSheikha fatimaStefanie avrilCase western reserve universityGlobal centerCleveland clinic centerCleveland clinic ledScience immunologyCleveland clinicTranslational hematologyPrecision immuno oncologyMubarak endowed chair

Health Beat: Alternative options for statin patients

Statins are one of the most prescribed drugs in the country. But what happens if you are statin-intolerant?

United statesStevene nissenHeart vascular thoracic instituteHeart vascularThoracic instituteCardiologist nissenCleveland clinic ledEmpedoic acid ezetimibe

Health Headlines: Plan B for statin-intolerant patients

Health Headlines: Plan B for statin-intolerant patients
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United statesStevene nissenHeart vascular thoracic institute at cleveland clinicIvanhoe newswireChief academic officerHeart vascularThoracic instituteCleveland clinicDoctor nissenCleveland clinic led