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Researchers decipher the molecular underpinning of exceptional responses in glioblastoma patients Despite access to some of the best possible medical care in the world, Senators John McCain and Edward Kennedy both died within 18 months of their diagnosis of glioblastoma, an aggressive form of brain cancer. While this deadly outcome typifies the nature of this disease, some glioblastoma patients see exceptional benefits from chemotherapy and survive beyond expectations. Why this happens has been revealed by researchers at the University of Minnesota in a new study published in the Proceedings of the National Academy of Sciences. Deciphering the molecular underpinning of these exceptional responses may hold the key to transforming the hope for miracles into the reality of an expected cure for glioblastoma patients, said Clark C. Chen, MD, PhD, Lyle French Chair in Neurosurgery and head of the Department of Neurosurgery at the University of Minnesota Medical School, who is also le

United statesSan diegoUniversity of minnesotaJun maClarkc chenEdward kennedyAaron sarverJudith varnerJohn mccainEmily hendersonUniversity of californiaM medical schoolUniversity of minnesota institute health informaticsDepartment of neurosurgeryProceedings of the national academy sciencesUniversity of minnesota medical school