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<p>The first randomised trial to investigate preventive ablation of a potential arrhythmogenic substrate associated with coronary chronic total occlusion (CTO) in patients at high risk of ventricular arrhythmias (VAs) &nbsp;reduces the risk of appropriate implantable cardioverter-defibrillator (ICD) therapy and unplanned hospitalisation in patients with no previously recorded VAs. The late-breaking science is presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).</p> <p>Principal investigator Dr. David Zizek of the University Medical Centre Ljubljana, Slovenia said: &ldquo;In everyday clinical practice, ventricular tachycardia (VT) ablation is still often regarded as a last resort in the management of patients with ischaemic cardiomyopathy. We hypothesised that ablation early in the course of the disease, when patients have a lower burden of comorbidities, might be associated with fewer periprocedural complications and impr

Slovenia generalUnited statesDavid zizekBiosense websterUniversity medical centre ljubljana grant numberEuropean society of cardiologyEuropean heart rhythm associationBoston scientificUniversity medical centre ljubljanaEuropean societyGrant numberLate breaking scienceCitycube berlin