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Jan 22, 2021
THURSDAY, Jan. 21, 2021 (HealthDay News) Regular use of aspirin is associated with a reduced risk for colorectal cancer (CRC) among those with initiation of aspirin before age 70 years, according to a study published online Jan. 21 in
JAMA Oncology.
Chuan Guo-Guo, M.Med., from Massachusetts General Hospital in Boston, and colleagues examined the correlation between aspirin use and risk for incident CRC among older adults in a pooled analysis conducted using the Nurses’ Health Study and the Health Professionals Follow-up Study. Data were included for 94,540 participants aged 70 years or older.
The researchers identified 1,431 incident cases of CRC during 996,463 person-years of follow-up. Compared with nonregular use, regular use of aspirin was associated with a significantly reduced risk for CRC at or after age 70 years after adjustment for other risk factors (hazard ratio, 0.80; 95 percent confidence interval, 0.72 to 0.90). The inverse association was only see