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Fluorescein Angiography Does Not Worsen Renal Dysfunction in Diabetic Retinopathy

A prospective study on patients with DR and CKD found no significant effect on renal function shortly after performing fluorescein angiography.

Investigating Real-world Consequences of Biases in Commonly Used Clinical Calculators

Cystatin C-Based Equation Accurate for Estimating Glomerular Filtration Rate

THURSDAY, Jan. 26, 2023 (HealthDay News) A cystatin C (cys)-based European Kidney Function Consortium (EKFC) equation has similar accuracy to the creatinine (cr)-based equation for estimating glomerular filtration rate (GFR), according to a study published in the Jan. 26 issue of the New England Journal of Medicine. Hans Pottel, Ph.D., from KU Leuven Campus

Temporal relationship between atherogenic dyslipidemia and inflammation and their joint cumulative effect on type 2 diabetes onset: a longitudinal cohort study | BMC Medicine

Concurrent atherogenic dyslipidemia and elevated inflammation are commonly observed in overt hyperglycemia and have long been proposed to contribute to diabetogenesis. However, the temporal relationship between them and the effect of their cumulative co-exposure on future incident type 2 diabetes (T2D) remains unclear. Longitudinal analysis of data on 52,224 participants from a real-world, prospective cohort study (Kailuan Study) was performed to address the temporal relationship between high-sensitivity C-reactive protein (hsCRP) and the atherogenic index of plasma (AIP, calculated as triglyceride/high-density lipoprotein) in an approximately 4-year exposure period (2006/2007 to 2010/2011). After excluding 8824 participants with known diabetes, 43,360 nondiabetic participants were included for further analysis of the T2D outcome. Cox regression models were used to examine the adjusted hazard ratios (aHRs) upon the cumulative hsCRP (CumCRP) and AIP (CumAIP) in the exposure period. In t

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