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Molnupiravir Does Not Reduce COVID-19-Related Hospitalization, Death
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Covid-19: Inhaled Steroids Show Benefit For Early Treatment in Select Patients
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Inhaled budesonide (Pulmicort), commonly used in asthma, helped COVID-19 outpatients at extra risk for severe illness recover more quickly relative to standard care in the pragmatic PRINCIPLE trial, British researchers said.
In an updated analysis of interim data, through March 25, duration of illness was significantly shorter in the 751 patients assigned to budesonide by 2.6 days (95% CI 1.0-4.7) versus standard care, reported Christopher C. Butler, FMedSci, of the University of Oxford in England, and colleagues writing in a
Median times to self-reported recovery were 10 days (interquartile range [IQR] 4-25 days) in the budesonide group compared with 13 days (IQR 4 days to no upper bound) among those receiving standard care (n=1,028) in the randomized open-label trial (probability of superiority 0.999).