IIT Madras & MIT Scientists Grow Human Brain Tissues from a 3D Printed Bioreactor indiaeducationdiary.in - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from indiaeducationdiary.in Daily Mail and Mail on Sunday newspapers.
Scientists developed a new 3D-printed microfluidic bioreactor to observe organoids as they grow. Photo by Ikram Khan
April 6 (UPI) Scientists have developed a new 3D-printed bioreactor, allowing researchers to observe tiny brains and other organoids as they grow.
The novel bioreactor featured in a new paper, published Tuesday in the journal Biomicrofluidics could help medical researchers develop new disease therapies and test experimental drugs.
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Over the last decades, scientists have gotten very good at culturing different types of human tissue and organoids, a miniaturized and simplified version of an organ, in the lab.
But challenges remain, and scientists are still trying to understand exactly how stem cells differentiate themselves into distinct tissue cells.
Credit: Ikram Khan
WASHINGTON, April 6, 2021 Scientists from MIT and the Indian Institute of Technology Madras have grown small amounts of self-organizing brain tissue, known as organoids, in a tiny 3D-printed system that allows observation while they grow and develop. The work is reported in
Biomicrofluidics, by AIP Publishing.
Current technology for real-time observation of growing organoids involves the use of commercial culture dishes with many wells in a glass-bottomed plate placed under a microscope. The plates are costly and only compatible with specific microscopes. They do not allow for the flow or replenishment of a nutrient medium to the growing tissue.