Nora Sun initiates and directs programs which introduce underrepresented high school students to scientific research with the goal of increasing cognitive diversity in science fields. She's looking forward to the fourth iteration of her ENVISION Research Competition, an accessible scientific research experience for female and genderqueer high school students.
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IMAGE: Researchers have precisely mapped the binding locations of over 400 proteins on the yeast genome using ChIP-exo. The method (top) uses an antibody to fish out a specific DNA-bound protein. view more
Credit: Pugh Lab, Cornell and Mahony Lab, Penn State
A massive effort to map the precise binding locations of over 400 different kinds of proteins on the yeast genome has produced the most thorough and high-resolution map of chromosome architecture and gene regulation to date. The study reveals two distinct gene regulatory architectures, expanding the traditional model of gene regulation. So-called constitutive genes, those that perform basic housekeeping functions and are nearly always active at low levels require only a basic set of regulatory controls; whereas those that that are activated by environmental signals, known as inducible genes, have a more specialized architecture. This finding in yeast could open the door to a better understanding of the
A new Penn State and Cornell study describes an effort to produce the most comprehensive and high-resolution map yet of chromosome architecture and gene regulation in yeast.