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Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders A team of researchers from the Agency for Science, Technology and Research s (A STAR) Genome Institute of Singapore (GIS) have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders. Their research was published in Nature Communications on 2 March 2021. One in seventeen people in the world suffers from some type of genetic disorder. Chances are, you or someone you know - a relative, friend, or colleague - is one of approximately 450 million people affected worldwide. Mutations responsible for these disorders can be caused by multiple mutagens - from sunlight to spontaneous errors in your cells. The most common mutation by far is the single-based substitution, in which a single-base in the DNA (such as G) is replaced by another base (such as C). Countless cystic fibrosis patients worldwide have C instead of G, leading to defective p

Kwei leongEmily hendersonAgency for scienceGenome institute of singaporeNature communicationsSenior research scientistGenome instituteC tog base editorChew wei leongYoung scientist awardPatrick tanExecutive directorCystic fibrosisGenetic disorderவெய் லியோங்எமிலி ஹென்டர்சன்