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$670K boost to study proteins involved in obesity, skin cancer, tuberculosis, more

Newly discovered threaded protein class explained | University of Hawaiʻi System News

The Pierced Lasso Topology is found in common items like crochet, belts and lifting straps. A recently discovered protein structure that controls the protein’s function and influences human health has been explained by University of Hawaiʻi at Mānoa researchers. Their findings were published in a new study, “Topological Twists in Nature,” by Trends in Biomedical Sciences. Topology refers to the way parts or components are arranged. The research by Department of Chemistry Assistant Professor Ellinor Haglund and graduate student Jennifer Michelle Simien involves the Pierced Lasso Topology ( PLT), which was discovered by Haglund within the past decade.

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