Allows sensitive detection of light elements, like hydrogen, fluorine, lithium and boron
Enables 3D chemical imaging of all elements with depth profiling resolution of less than 10 nm and lateral resolution of less than 50 nm
Can be used with leading commercial FIB-SEM microscopes without affecting the quality of images
Allows unequivocal elemental identification with an increased mass resolving power
Enables isotopic imaging for experiments to analyze diffusion, transport, or reaction mechanisms
Advancing FIB-SIMS Without Compromise
The fibTOF Adds 3D Chemical Imaging to FIB-SEM Microscopes
Secondary ion mass spectrometry, or SIMS, is a proven method where an energetic ion beam is used for sample sputtering, causing the ejection of both charged particles (secondary ions) and neutral particles.
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Every movement in the human body from lifting our arms to our beating hearts is regulated in some way by signals from our brains. Until recently, scientists often tracked and understood that brain-body communication only after the fact, sort of like listening to a voicemail as opposed to being on a call.
But researchers at Northeastern have developed a new type of nanosensor that allows scientists to image communication between the brain and the body in real time. They now can listen in on the call.
Heather Clark, professor of bioengineering and chemistry at Northeastern, and
James Monaghan, associate professor of biology, along with colleagues at Northeastern and researchers from the University of California, San Francisco, developed a DNA-based nanosensor that detects a specific neurotransmitter, acetylcholine, as it’s released and picked up by target cells in living animals. They