«Секретные сведения скрываются от губернаторов» kommersant.ru - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from kommersant.ru Daily Mail and Mail on Sunday newspapers.
Информация о будущей аллергии содержится в первом кале младенца vesti.ru - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from vesti.ru Daily Mail and Mail on Sunday newspapers.
Baby s first poo helps predict immune health and risk of allergy The composition of a baby s first poo, called the meconium, is associated with whether or not a child will develop allergies within their first year of life, according to new research.
The study, published in
Cell Reports Medicine, suggests that the development of a healthy immune system and microbiota may actually start well before a child is born, and signals that the tiny molecules an infant is exposed to in the womb play a fundamental role in future health. Our analysis revealed that newborns who developed allergic sensitization by one year of age had significantly less rich meconium at birth, compared to those who didn t develop allergic sensitization, says the study s senior co-author Dr. Brett Finlay, a professor at the Michael Smith Laboratories and departments of biochemistry and molecular biology, and microbiology and immunology at University of British Columbia (U
email article
Contents of baby s first stool were a biomarker for early-life allergy risk in a study of 100 infants.
Infants who developed IgE-mediated atopy by age 1 showed a significantly poorer environment in their meconium the fecal matter accumulated prior to birth and typically expelled within a few days of delivery for microbiotal development compared with those without signs of allergic sensitization, reported Charisse Petersen, PhD, of the University of British Columbia in Vancouver, and colleagues in
While the metabolomic compositions didn t differ starkly enough in this study to serve as a clinical prognostic tool a meconium metabolite panel showed an area under the receiver operating characteristic curve (AUC) of 0.59 the study s findings do provide another indication that intestinal bacteria play a role in allergic sensitization and may ultimately find clinical application.