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DNA Damage Repair System Detailed in Novel Map

DNA Damage Repair System Detailed in Novel Map
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Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

A new map reveals the complicated world in which cells seek to repair damaged DNA

A new map reveals the complicated world in which cells seek to repair damaged DNA
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Researchers reveal the cooperative effect of multiple oscillatory signals in biological systems

Oscillatory dynamics in fundamental biological processes, such as circadian clocks, segmentation, and transcription factor responses, requires precise quantitative control for proper cell regulation and fate decisions.

Live Cells Oscillators Interact for Complex Behaviors

Live Cells Oscillators Interact for Complex Behaviors
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