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Exploring New Therapeutic Paths for Bone Repair

Exploring New Therapeutic Paths for Bone Repair
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United kingdomHelen mcgettrickHelen dunsterJonathan lewisAmy naylorJames edwardsBritish society for research onYuti chernajovsky biomedical research foundationUniversity of oxfordNuffield department of orthopaedicsMusculoskeletal sciencesInstitute of inflammationResearch councilBusiness developmentUniversity of birminghamPeptide inhibitor

Experimental Therapeutics Center Transforms Lab Finds into Treatments

Experimental Therapeutics Center Transforms Lab Finds into Treatments
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United statesTom sellersArpit dheerajChristine torres hicks dhanirSanjay malhotraShivaani kummarChristine torres hicksDiscovery biotech incKnight cancer instituteSchool of medicineTranslational sciencesOregon health science universityNational centerBiomedical innovation programNational institutes of healthExperimental therapeutics

Study finds novel therapeutic avenues in bone repair

Study finds novel therapeutic avenues in bone repair
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United kingdomJonathan lewisHelen mcgettrickAmy naylorJames edwardsBritish society for research onMusculoskeletal sciencesUniversity of birminghamUniversity of oxfordYuti chernajovsky biomedical research foundationResearch councilInstitute of inflammationNuffield department of orthopaedicsPeptide inhibitorTrans endothelial migrationCell reports medicine

Cancer drug shows powerful anti-tumor activity in animal models of several different tumor types

Behind the scenes, as tumors progress and gain resistance to treatment, a protein called YB-1 quietly gives directions. Now, researchers at Oregon Health & Science University have developed a first-of-its-kind drug that inhibits YB-1, effectively silencing those orders.

United statesShivaani kummarArpit dheerajSanjay malhotraOregon health science universitySchool of medicineKnight cancer instituteCell reports medicineOregon healthScience universityExperimental therapeuticsCell reports

Naturally-occurring peptide shows promise as new therapeutic in bone repair

Birmingham researchers have shown that PEPITEM, a naturally-occurring peptide (small protein), holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct advantages over existing drugs.

Helen dunsterHelen mcgettrickAmy naylorJonathan lewisJames edwardsKathryn frostBusiness developmentInstitute of inflammationMusculoskeletal sciencesUniversity of birminghamNuffield department of orthopedicsUniversity of oxfordPeptide inhibitorTrans endothelial migrationCell reports medicineNuffield department