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Potential Approaches to Treatment Switching in HR+/HER2- mBC

Experts share how they approach management of patients with disease progression on first-line endocrine therapy, with a focus on ESR1 mutation testing and identifying who might be suitable for treatment with the oral SERD elacestrant.

Selecting Endocrine Therapy in BRCA1/BRCA2+ Breast Cancer

Experts in breast oncology discuss how they select endocrine therapy in BRCA1/BRCA2+ breast cancer.

Real-World Data on CDK4/6 Inhibitors in HR+/HER2- Metastatic Breast Cancer and Ongoing Trials

Experts on HR+/HER2- breast cancer review recent real-world data on CDK4/6 inhibitors and share excitement about first-line trials that have not yet read out.

Implementing Trial Data to Our Practice

Stephanie Graff, MD, and Rachel Layman, MD, discuss how they would apply the results of the monarchE trial to clinical case scenarios.

Dosing CDK 4/6 Inhibitors

Rachel Layman, MD, summarizes how to dose CDK4/6 inhibitors in different clinical settings.

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