Researchers at the Institute for Basic Science (IBS) in South Korea have made a significant breakthrough in the field of asymmetric synthesis of β-lactams, which are prominent in bioactive compounds. Their innovative approach employs nickel and hydrocarbon sources that are abundant on Earth to access value-added β-lactam products. The employment of nickel-hydride catalysis and alkenyl dioxazolone derivatives gives rise to the selective formation of four-membered lactam products. This development offers a direct route to achieve enantioselective synthesis of β-lactams.
Breakthrough in β-lactam synthesis using nickel catalysts
wn.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from wn.com Daily Mail and Mail on Sunday newspapers.
Observing The Long-Postulated Intermediate Of Catalytic Amination Reactions
chemicalonline.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from chemicalonline.com Daily Mail and Mail on Sunday newspapers.