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New insights from Canadian researchers help explain how the PCSK9 protein degrades low-density lipoprotein (LDL) and its role in atherosclerosis and cancer.
In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they've found the molecular mechanism by which the protein PCSK9 degrades the receptor of low density lipoproteins, the richest cholesterol particles in the bloodstream.