Demonstrated Significant Reduction of Pain and Cartilage Degeneration in Rat Osteoarthritis Model
DURHAM, N.C., May 25, 2021 (GLOBE NEWSWIRE) Bioventus Inc. ( BVS) (âBioventusâ or the âCompanyâ), a global leader in innovations for active healing, announced human placental tissue, prepared as a particulate composition, termed PTP-001, was shown to contain an array of beneficial growth factors, cytokines and anti-inflammatory molecules, which significantly reduced pain and cartilage degeneration in a rat osteoarthritis (OA) model. These findings were published on May 19, 2021 in
The in vivo activity of PTPâ001 on joint pain and histopathology was evaluated in a rat model of OA that was induced surgically by destabilization of the medial meniscus. In the model, PTPâ001 significantly reduced pain responses throughout six weeks postâdosing as compared to a saline treatment. The magnitude and duration of pain reduction following a single intra-articu