MSCI's broadest index of Asia-Pacific shares outside Japan lost 0.1%, hovering just above the two-year low hit on Tuesday, while US Nasdaq futures shed 0.3%.
The US economy may be heading into a recession, according to a commonly accepted indicator, after inflation there surged to a more-than-expected 40-year peak, increasing bets for a 100 basis points rate hike by the Federal Reserve later this month.