Sicker patients in the EAST-AFNET4 trial showed a pronounced survival advantage from early rhythm control, compared with a rate-control-first approach, while those with fewer comorbidities missed out.
The way sinus rhythm is restored in patients with atrial fibrillation might make a difference to risk for later dementia, suggests a cohort study that still leaves plenty of questions.
Early restoration of sinus rhythm by cardioversion or ablation should be vigorously attempted to improve reverse remodeling and improve valvular function, researchers say.
A phase 2 study shows promising benefits and safety with a new leadless pacemaker, delivering effective right ventricular pacing with a retrievable device.