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PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma

PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma
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Proteostat aggresomeDrug administrationCelltiter glo luminescent cell viabilityGene ontologyDrug sensitivityCancer therapeutics response portalCancer cell line encyclopedia

Epigenetic drug-sensitive biomarkers for cancer

Researchers perform an epigenome-wide multi-omic high-throughput screen to identify actionable epigenetic drug-sensitive biomarkers.

Giovanni cancemi shutterstockCommunications biologyGiovanni cancemiDrug sensitivityCancer genome atlasCancer therapeutics response portalEnhancer linkingExpression relationshipsNa methylationEne expression

Researchers discover a weak spot that makes multi-drug resistant tumors vulnerable

One of the greatest challenges facing cancer researchers is to understand why some patients don't respond to treatments.

Oscar fernandez capetilloEmily hendersonSpanish national cancer research centreGenomic instability groupSpanish association against cancerSpanish ministry of scienceCaixa foundationInstability groupCancer cell line encyclopediaCancer therapeutics response portalSpanish ministry