Brian M. Slomovitz, MD, discusses the evaluation of letrozole and ribociclib from the phase 2 GOG 3026 trial in recurrent low-grade serous ovarian carcinoma.
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The Impact of COVID-19 on Oncology Clinical Trials
Since the beginning of the COVID-19 pandemic in early 2020, the diagnosis, treatment and surveillance of cancer has been transformed globally. The heavy demand for resources, exacerbated by limited excess health system capacity, means that health care systems have become quickly overwhelmed and hospitals have become sources for virus transmission.
Furthermore, a severe COVID-19 phenotype is seen more commonly in men and older, more comorbid patients.
1 Indeed, this is the same comorbidity profile common for many patients with genitourinary malignancies. The need for repeated in-person interactions has hampered the ongoing accrual and conduct of prospective research during the COVID-19 pandemic. In many regions, accrual to prospective studies has entirely stopped as a result of the pandemic. In jurisdictions which are particularly hard hit, many research personnel and research-related resources have been re-directed and re-deploy