New study can help determine effectiveness of chemotherapy in patients with bladder cancer
In patients with bladder cancer, chemotherapy effectiveness is partially determined by the body s immune system response to the malignancy. This is the conclusion of research conducted by a team of scientists from Charité - Universitätsmedizin Berlin and the Berlin Institute of Health.
The findings, which have been published in
Science Translational Medicine, can be used to predict treatment success and may increase survival in patients with bladder cancer.
Bladder cancer is one of the ten most common types of cancer in Germany, and one of the five most common cancers in men. Nationwide, the disease affects approximately 30,000 people a year. The risk of cancer spreading (metastasizing) is particularly high once it invades the muscle layer inside the bladder wall.
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IMAGE: The research team plans to study patients with bladder cancer and other cancers to establish whether cell therapy might be used to encourage and enhance the immune system s fight against. view more
Credit: Photo: Hirscher/Charité
In patients with bladder cancer, chemotherapy effectiveness is partially determined by the body s immune system response to the malignancy. This is the conclusion of research conducted by a team of scientists from Charité - Universitätsmedizin Berlin and the Berlin Institute of Health. The findings, which have been published in
Science Translational Medicine , can be used to predict treatment success and may increase survival in patients with bladder cancer.
A new study by Markey researchers shows a higher-than-average rate of DACH1 mutations in Kentucky patients with endometrial cancer.
LEXINGTON, Ky. (Jan. 12, 2020) A new study by University of Kentucky Markey Cancer Center researchers shows that DACH1 mutations are prevalent in Kentucky patients with endometrial cancer, suggesting that DACH1 may be a candidate biomarker for future trials with immunotherapy.
DACH1 is a transcriptional repressor and tumor suppressor gene that is frequently mutated in other cancers, including melanoma, bladder and prostate cancer. The loss of DACH1 expression is also associated with poor prognosis and reduced survival in women with uterine cancer.
Published in PLOS One, the study sought to determine the frequency of DACH1 mutations in patients with endometrial cancer in Kentucky. Using the Oncology Research Information Exchange Network (ORIEN), a personalized medicine consortium that Markey joined in 2017, researchers examined clinical and genomic
Fujitsu Develops Technology to Discover Characteristic Causal Relationships of Individual Data in Medicine, Marketing, and More JCN Newswire
2020-12-17
KAWASAKI, Japan, Dec 17, 2020 - (JCN Newswire) - Fujitsu Laboratories, Ltd. has successfully developed a technology that uses AI to discover the characteristic cause-and-effect relationships in various pieces of data relating to people and things in a variety of fields, with possible applications in medicine, marketing, manufacturing, and more.
Image of the developed technology
The technology specifically addresses the need to isolate and identify characteristics from data in different real-world scenarios. In the medical field, for example, it is necessary to identify the characteristic genes that affect the development of cancer in individual patients. In the field of marketing, sales representatives need to find the characteristic factors that lead individual customers to make a purchase. Fujitsu has developed a tech
Fujitsu Develops Technology to Discover Characteristic Causal Relationships of Individual Data in Medicine, Marketing, and More
KAWASAKI, Japan, Dec 17, 2020 – (JCN Newswire) – Fujitsu Laboratories, Ltd. has successfully developed a technology that uses AI to discover the characteristic cause-and-effect relationships in various pieces of data relating to people and things in a variety of fields, with possible applications in medicine, marketing, manufacturing, and more.
Image of the developed technology
The technology specifically addresses the need to isolate and identify characteristics from data in different real-world scenarios. In the medical field, for example, it is necessary to identify the characteristic genes that affect the development of cancer in individual patients. In the field of marketing, sales representatives need to find the characteristic factors that lead individual customers to make a purchase. Fujitsu has developed a technology to discover the charact