so, lots of toxic . amyloid protein. you can see it clearly in these scans. this patient starts with a lot of amyloid shown in green, yellow and red but after six months on donanemab, most of the amyloid has been removed. this is really significant. i mean, this is one of the biggest breakthroughs, insomuch as this - disease is a pandemic. it s getting more i and more common. and being able to both - remove the amyloid protein and demonstrate that that. correlates with the slowing, or hopefully steadying - of symptoms, is life changing. so a moment of hope? a moment of enormous hope. this is fantastic. hello. are you ready to come through? yes. all right. donanemab could be licensed here within a year, butjanet north is hoping to get it sooner, as part of the next stage of trials. could you tell me what year it is? oh, dear.
disease is a pandemic. it s getting more i and more common. and being able to both - remove the amyloid protein and demonstrate that that. correlates with the slowing, or hopefully steadying - of symptoms, is life changing. so a moment of hope? a moment of enormous hope. this is fantastic. hello. are you ready to come through? yes. all right. donanemab could be licensed here within a year, butjanet north is hoping to get it sooner, as part of the next stage of trials. could you tell me what year it is? oh, dear. she sighs no. 2004, i was going to say, but it s 2020 something, isn t it? 2024? 0k. janet, who s 76, says alzheimer s means she no longer remembers how to use a computer or how to cook.
in alzheimer s, a rogue protein called amyloid builds up around neurons, destroying connections. donanemab is an antibody which binds to amyloid. this prompts immune cells to attack and clear amyloid from the brain. so, lots of toxic amyloid protein. you can see it clearly in these scans. this patient starts with a lot of amyloid shown in green, yellow and red but after six months on donanemab, most of the amyloid has been removed. this is really significant. i mean, this is one of the biggest breakthroughs, insomuch as this disease is a pandemic. it s getting more and more common. and being able to both remove the amyloid protein and demonstrate that that correlates with the slowing, or hopefully steadying of symptoms, is life changing. so a moment of hope? a moment of enormous hope. this is fantastic. hello. are you ready to come through? yes. all right. donanemab could be licensed here within a year, butjanet north is hoping to get it sooner,
heuo. are you ready to come through? yes. all right. donanemab could be licensed here within a year, butjanet north is hoping to get it sooner, as part of the next stage of trials. could you tell me what year it is? oh, dear. she sighs no. 2004, i was going to say, but it s 2020 something, isn t it? 2024? 0k. janet, who s 76, says alzheimer s means she no longer remembers how to use a computer or how to cook. i can t make things nice. i can t cook as i want to cook. i have no timing ability, and that s crucial. erm, itjust drives me potty, because i can t do it. but before any patient gets donanemab, they have to have one of these a pet scan, a specialised
donanemab is an antibody which binds to amyloid. this prompts immune cells to attack and clear amyloid from the brain. so, lots of toxic amyloid protein. you can see it clearly in these scans. this patient starts with a lot of amyloid shown in green, yellow and red but after six months on donanemab, most of the amyloid has been removed. this is really significant. i mean, this is one of the biggest breakthroughs, insomuch as this disease is a pandemic. it s getting more and more common. and being able to both remove the amyloid protein and demonstrate that that correlates with the slowing, or hopefully steadying of symptoms, is life changing. so a moment of hope? a moment of enormous hope. this is fantastic. hello. are you ready to come through? yes. all right. donanemab could be licensed here within a year, butjanet north is hoping to get it sooner,