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Benchtop Research Lowers Barrier to Clinical Translation

Scientists at the Australian National Phenome Centre (ANPC) at Murdoch University have detected and quantified newly discovered biomarkers of SARS-CoV-2 acute infections and of ‘Long COVID’ using a benchtop Fourier Transform-nuclear magnetic resonance (FT-NMR) spectrometer with a permanent magnet, effectively  lowering clinical translation of this epidemiological and diagnostic research technology. Click to read more.

Bruker fourierJeremy nicholsonBruker avance ivdrAustralian national phenome centreMurdoch universityFourier transform nuclearProfessor jeremy nicholsonBruker avance

NMR metabolic profiling on early identification and severity prediction of COVID-19*

Even though COVID-19 is a respiratory disease caused by the SARS-Cov-2, it can also affect other organs, leading to neurologic, renal, hepatic, and vascular damage. In the most severe cases, it frequently results in multi-organ damage

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Monitoring the relationship between Endothelial Lipase and HDL by NMR

High-density lipoprotein (HDL) performs anti-oxidative, anti-inflammatory, and cholesterol efflux functions. Therefore, a high level of HDL is considered beneficial to protect against atherosclerosis, the buildup of plaque in the arteries, which can lead to a heart attack or stroke.

Bruker ivdrBruker biospinShutterstock marynaolyakResearch useInternational journal of molecular sciencesBruker biospin groupSponsored contentBruker avanceAvance neoEndothelial lipase modulated paraoxonaseArylesterase activityContent policyNews medical netHigh density lipoprotein hdl

1H-NMR urinary profiling shows potential for SMA diagnosis*

Despite urinary biomarkers being successfully used to diagnose and monitor a range of central nervous system disorders, including demyelinating, neurodegenerative, and motor neuron diseases, disease-specific metabolomic changes have not been identified for spinal muscular atrophy (SMA).

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TMS is Superior to Residual CHCl3 for Use as the Internal Reference for Routine 1H NMR Spectra Recorded in CDCl3

TMS is Superior to Residual CHCl3 for Use as the Internal Reference for Routine 1H NMR Spectra Recorded in CDCl3
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