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Alabama research finds higher false positives in DNA tests for Black participants
Updated Jan 31, 2021;
African Americans who participated in an Alabama effort to increase access to genetic health screenings had higher rates of false positives for markers related to cancer and heart disease, according to researchers.
Genetic testing has become increasingly widespread, with direct-to-consumer companies like 23andMe offering DNA reports about ancestry and health traits. Black participants are more likely to get inaccurate results that may lead to anxiety and invasive screenings for cancer, said Dr. Greg Barsh, faculty investigator at HudsonAlpha Institute for Biotechnology in Huntsville.
“The accuracy of the technology that we’re using to identify genomic risk factors varies according to ancestry,” Barsh said. “In particular, individuals with some African ancestry, there’s a higher risk of false positives. DNA that is of African origin needs to be thought about and treat