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Study finds two antibiotics for children with sinusitis equally effective, but one had fewer side effects

Study finds two antibiotics for children with sinusitis equally effective, but one had fewer side effects
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United statesKrista huybrechtsBrigham division of pharmacoepidemiologyNational institutes of healthMass general brighamTimothy savageEunice kennedy shriver national instituteChild healthHuman developmentNational institutes

Study finds two antibiotics for children with sinusitis equally effective, but one has fewer side effects

Study finds two antibiotics for children with sinusitis equally effective, but one has fewer side effects
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United statesTimothyj savageJournal of the american medical associationBrigham division of pharmacoepidemiologyTimothy savageTreatment failureAdverse events after amoxicillin clavulanatePediatric acute sinusitisAmerican medical

Study finds two antibiotics for children with

Acute sinusitis is one of the most common causes for children to be put on antibiotic medications, with patients in the United States filing nearly 5 million antibiotic prescriptions every year to treat the condition. The drugs amoxicillin and amoxicillin-clavulanate make up most of those prescriptions, but there is a lack of consensus on which should be first-line for children.

United statesKrista huybrechtsBrigham division of pharmacoepidemiologyNational institutes of healthMethod of researchMass general brighamTimothy savageEunice kennedy shriver national instituteChild healthHuman developmentNational institutesAdverse eventsPediatric acute

Many top-selling brand-name drugs in Medicare may provide little added therapeutic benefit

Brand-name drugs cost two to three times more in the U.S. than in other countries, but many of the top-selling brand name drugs may provide little added therapeutic benefit.

Emily hendersonAarons kesselheimAlexanderc egilmanCenters for medicareBrigham division of pharmacoepidemiologyMass general brighamFirst authorBrigham divisionInflation reduction actPrescription drug

Majority of Best-selling Medicare Drugs Provide Limited Therapeutic Benefit

Majority of Best-selling Medicare Drugs Provide Limited Therapeutic Benefit
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Aarons kesselheimAaron kesselheimAlexanderc egilmanBrigham division of pharmacoepidemiologyCommonwealth fundCenters for medicareMass general brighamBrigham divisionInflation reduction actTherapeutic benefitTop selling brand name drugs