ANI | Updated: Jan 17, 2021 23:38 IST
Washington [US], January 17 (ANI): A new research has indicated that itching often doesn t respond to antihistamines because the itch signals are being carried to the brain along a previously unrecognized pathway that current drugs don t target.
New research from Washington University School of Medicine in St. Louis indicates that allergens in the environment often are to blame for episodes of acute itch in eczema patients.
The new findings, published in the journal Cell, point to a possible new target and strategy to help eczema patients cope with those episodes of acute and severe itch. Years ago, we used to think that itch and pain were carried along the same subway lines in the nerves to the brain, but it turned out they weren t, and these new findings show there s another pathway entirely that s causing these episodes of acute itching in eczema patients, said principal investigator Brian S. Kim, M
Study shows why antihistamine drugs fail to control severe itch in eczema patients
In addition to a skin rash, many eczema sufferers also experience chronic itching, but sometimes that itching can become torturous. Worse, antihistamines the standard treatment for itching and allergy often don t help.
New research from Washington University School of Medicine in St. Louis indicates that allergens in the environment often are to blame for episodes of acute itch in eczema patients, and that the itching often doesn t respond to antihistamines because the itch signals are being carried to the brain along a previously unrecognized pathway that current drugs don t target.
Acute Itching in Eczema Patients Linked to Environmental Allergens Details 15 January 2021
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In addition to a skin rash, many eczema sufferers also experience chronic itching, but sometimes that itching can become torturous.
In addition to a skin rash, many eczema sufferers also experience chronic itching, but sometimes that itching can become torturous. Worse, antihistamines the standard treatment for itching and allergy often don’t help.
New research from Washington University School of Medicine in St. Louis indicates that allergens in the environment often are to blame for episodes of acute itch in eczema patients, and that the itching often doesn’t respond to antihistamines because the itch signals are being carried to the brain along a previously unrecognized pathway that current drugs don’t target.
Newly identified pathway explains why antihistamine drugs often don’t work to control severe itch
January 14, 2021 SHARE Research at Washington University School of Medicine in St. Louis indicates that cells in the blood called basophils (brown in illustration) can react to allergens (round honeycomb shapes) in the environment and send itch signals to nerve cells, leading to episodes of severe itch in eczema patients that can t be treated by antihistamines. (Image: Madison Mack)
In addition to a skin rash, many eczema sufferers also experience chronic itching, but sometimes that itching can become torturous. Worse, antihistamines the standard treatment for itching and allergy often don’t help.