In normal breast development, estrogen stimulates and androgen inhibits growth at puberty and throughout adult life. Abnormal estrogen activity is responsible for the majority of breast cancers, but the role of androgen activity in this disease has been controversial.
Androgens were historically used to treat breast cancer, but knowledge of hormone receptors in breast tissue was rudimentary at the time and the treatment s efficacy misunderstood. Androgen therapy was discontinued due to virilising side effects and the advent of anti-estrogenic endocrine therapies.
While endocrine therapy is standard-of-care for estrogen receptor positive breast cancer, resistance to these drugs are the major cause of breast cancer mortality.
New discovery in breast cancer treatment
Researchers at the University of Adelaide have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease.
Published today in Nature Medicine, the international study conducted in collaboration with the Garvan Institute of Medical Research, looked at the role of androgens – commonly thought of as male sex hormones but also found at lower levels in women – as a potential treatment for estrogen receptor positive breast cancer.
Watch a video explainer about the new study at – https://youtu.be/NYalzv4C35U
Support Notes: Dec. 20-26
Times Record Staff
Al-Anon: 12 step support groups for families and friends of alcoholics. Info line (479) 441-9705 or (888) 425-2666.
• Get A Life Step Study: 12 p.m. Monday at Community Bible Church, 9201 Dallas St., Fort Smith (near playground entrance). Call (479) 806-0184.
• Adult Child: 8 p.m. Monday at Midland Heights United Methodist Church, 3500 N. Sixth St., Fort Smith. Call (479) 459-8756.
• Steps to Serenity Step Study: 5:30 p.m. Tuesday at Community Bible Church, 9201 Dallas St., Fort Smith (near office entrance). Call (479) 650-2762 or (479) 461-6486.
• 4U2: 6 p.m. Tuesday at 426 Holden Street in Booneville. Call (479) 225-9150.
• Safe Landing: 6:30 p.m. Tuesday at Trinity United Methodist Church, 1601 E. Shantel Smith Blvd., Muldrow.
Support Notes: Dec 13-19 - Lifestyle - Pine Bluff Commercial pbcommercial.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from pbcommercial.com Daily Mail and Mail on Sunday newspapers.
anybody. so i think when they see that the chemistry council wrote the bill, that 450 groups, including the asbestos group, the breast cancer group, and i could go on with, you know, so long. i have them at the hearing tomorrow. all the groups that oppose it. it s unprecedented. i think maybe my colleagues will rethink it. look, the bill is a udall-vitter-inhofe bill. i want to tell you something, rachel, the rating of vitter by environmental groups is 5%. he votes against the environment 95% of the time. the rating of jim inhofe is 5%. i guess they were good 5% of the time. so the bottom line here is, this is a bad bill, written by the chemistry council. it is a weak bill, and it pre-empts state action. it s very, very dangerous. it s very, very serious, and