SARS-CoV-2 induces endogenous retrovirus envelope in cultured lymphocytes from a subset of healthy donors Results achieved with successive variants of SARS-CoV-2 until Omicron waves
Press Release New study published in Cell Press demonstrates that SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W. | May 3, 2023
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GeNeuro: Researchers Detect HERV-W ENV in COVID-19 Patients and Link Expression to Disease Severity
Data published in the Lancet s EBioMedicine shows that the pathogenic envelope protein of the human endogenous retrovirus W (HERV-W ENV) is found on lymphocytes of hospitalized patients with COVID-19, and that its level of expression is associated with disease severity.
HERV-W ENV s pro-inflammatory properties thought to act as an accelerant of the activation of the innate immune system, fueling the severity of COVID-19 evolution and impacting long term recovery.
Preliminary data available on Research Square also shows HERV-W ENV expression in lymphocytes following in vitro exposure to SARS-CoV-2 in about 20% of healthy blood donors, suggesting individual susceptibility.
GeNeuro Receives French State Grant to Accelerate Research Into the Role of HERV Proteins in COVID-19 wallstreet-online.de - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from wallstreet-online.de Daily Mail and Mail on Sunday newspapers.