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Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

Dana farber cancer instituteUnited statesUnited kingdomBoston universityRichard bowenAaron mossLoren walenskyRobert daveyMassachusetts consortium on pathogen readinessMicrobiology at boston universityBoston university national emerging infectious diseases laboratoriesColorado state universityNational institutes of healthBlood disorders centerNature communicationsFarber cancer

Novel compound protects against infection by virus that causes COVID-19, preliminary studies show

Novel compound protects against infection by virus that causes COVID-19, preliminary studies show
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Dana farber cancer instituteUnited statesUnited kingdomBoston universityRichard bowenAaron mossRobert daveyLoren walenskyMicrobiology at boston universityBlood disorders centerColorado state universityNature communicationsBoston university national emerging infectious diseases laboratoriesCov urbaniPrincipal investigatorLinde program

Novel Compound Shields Against COVID-19 in Preliminary Tests

Novel Compound Shields Against COVID-19 in Preliminary Tests
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United statesBoston universityUnited kingdomDana farber cancer instituteRichard bowenAaron mossRobert daveyLoren walenskyBlood disorders centerColorado state universityNational institutes of healthMicrobiology at boston universityBoston university national emerging infectious diseases laboratoriesMassachusetts consortium on pathogen readinessNature communicationsPrincipal investigator

Novel Compound Protects Against Infection by Virus that Causes COVID-19, Preliminary Studies Show

• Stapled lipopeptides successfully deter infection by the SARS-CoV-2 virus and reduce the severity of COVID-19 in tests with hamsters

Dana farber cancer instituteUnited statesBoston universityUnited kingdomAaron mossLoren walenskyRichard bowenRobert daveyMicrobiology at boston universityNature communicationsNational institutes of healthMassachusetts consortium on pathogen readinessBlood disorders centerColorado state universityBoston university national emerging infectious diseases laboratoriesPrincipal investigator

Novel Compound Protects Against Infection by Virus that Causes COVID-19, Preliminary Studies Show

Novel Compound Protects Against Infection by Virus that Causes COVID-19, Preliminary Studies Show
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United kingdomUnited statesBoston universityDana farber cancer instituteLoren walenskyRobert daveyRichard bowenAaron mossNature communicationsMicrobiology at boston universityColorado state universityBoston university national emerging infectious diseases laboratoriesMassachusetts consortium on pathogen readinessBlood disorders centerNational institutes of healthPrincipal investigator