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(For Immediate Release Singapore January 28, 2021) In the phase II CodeBreak 100 trial, sotorasib provided durable clinical benefit with a favorable safety profile in patients with pretreated non-small cell lung cancer (NSCLC) and who harbor KRAS p.G12C mutations, validating CodeBreak 100 s phase I results, according to research presented today at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.
Outcome in patients with advanced NSCLC on second- or third-line therapies is poor, with a response rate of less than 20% and median progression-free survival of fewer than four months. Approximately 13% of patients with lung adenocarcinomas harbor KRAS p.G12C mutations.
Sotorasib Provides Durable Clinical Benefit for Patients with NSCLC and KRAS Mutations
Exciting New Research to be Presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer’s Presidential Symposium
SINGAPORE, Jan. 28, 2021 (GLOBE NEWSWIRE) In the phase II CodeBreak 100 trial, sotorasib provided durable clinical benefit with a favorable safety profile in patients with pretreated non-small cell lung cancer (NSCLC) and who harbor
KRAS p.G12C mutations, validating CodeBreak 100’s phase I results, according to research presented today at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.
Outcome in patients with advanced NSCLC on second- or third-line therapies is poor, with a response rate of less than 20% and median progression-free survival of fewer than four months. Approximately 13% of patients with lung adenocarcinomas harbor
These updates are republished press releases and communications from members of the Science|Business Network
Amgen CEO: Greater U.S.-China collaboration will accelerate fight against cancer
Last month, Amgen CEO Bob Bradway helped kick off a high-level roundtable discussion focused on accelerating cancer research through greater collaboration between the U.S. and China. Held November 18 as part of the Bloomberg New Economy Forum, the Moonshot Roundtable discussion was co-facilitated by the Honorable Kevin Rudd, President of the Asia Society Policy Institute and former Prime Minister of Australia, and Dr. Bob Li, Physician Ambassador to China and Asia-Pacific at Memorial Sloan Kettering Cancer Center. The session brought together senior leaders from industry, academia and government.
The 2020 WCLC Presidential Symposium features:
National Lung Cancer Screening Program in Taiwan: The TALENT Study (Abstract 3309), Pan-Chyr Yang, M.D., from the National Taiwan University College of Medicine, Taipei/Taiwan.
International Tailored Chemotherapy Adjuvant Trial: ITACA (Abstract 1820) with Dr. Silvio Novello, University of Torino at San Luigi Gonzaga Hospital, Orbassano, Italy.
Surgical and Clinical Outcomes with Neoadjuvant Atezolizumab in Resectable Stage IB-IIIB NSCLC: LCMC3 Trial Primary Analysis (Abstract 3195) with Jay M. Lee, M.D., Ronald Reagan UCLA Medical Center in Los Angeles.
Registrational Phase 2 Trial of Sotorasib in Kras P. G12C Mutant NSCLC: First Disclosure of the CodeBreak100 Primary Analysis (Abstract 3037) with Bob Li, M.D., Memorial Sloan Kettering Cancer Center in New York City.