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Despite enduring disparities, stem cell transplants expand across all races, ethnicities

The amount of autologous and allogeneic hematopoietic stem cell transplants for hematologic disorders has increased over time in tandem with longer survival, according to results of an observational study. Researchers observed improvements across all racial and ethnic groups but found that disparities related to treatment outcomes still exist.

United statesByjosh friedmanNandita kheraMindy valcarcelMarrow transplant researchAmerican society of transplantationInternational bloodNational marrow donor programAfrican americanBlood advBlood advancesHispanic african americanMayo clinicHispanic african americansAfrican americansNative american

Metformin use linked to lower risk for rare blood cancer

Individuals prescribed the antidiabetes treatment metformin less likely developed a myeloproliferative neoplasm —potentially also reducing a person’s chances for developing certain cancers — according to data published in Blood Advances.Metformin is a therapy used by patients with type 2 diabetes to treat high blood sugar by increasing the efficacy of insulin.

Daniel tuyet kirstensenBymatthew shinkleMindy valcarcelAarhus university hospitalAalborg university hospitalBlood advStidsholt rougTuyet kirstensen

Aspaveli® (pegcetacoplan) approved in Europe for use among treatment naïve adult patients with PNH

Aspaveli® (pegcetacoplan) approved in Europe for use among treatment naïve adult patients with PNH
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United statesUnited kingdomPrnewswire sobiAspaveli empaveliAnn hematolSobi investor relations teamEuropean unionEuropean commissionLydia abad franchMedical affairsChief medical officerNorth americaMiddle eastSobi mediaBlood advPatients with

Mapping genotypes to chromatin accessibility profiles in single cells

Mapping genotypes to chromatin accessibility profiles in single cells
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Van egerenBlood advStem cellA mediated polo likeCell sciHwee park

Liso-cel CAR-T cost-effective as second-line treatment for advanced lymphoma

Liso-cel CAR-T cost-effective as second-line treatment for advanced lymphoma
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United statesMindy valcarcelBymatthew shinkleBristol myers squibbBlood advSouthern californiaKeck school