The exhibition, titled Gratitude, will first go on display in Birmingham’s Chamberlain Square next month.
It will include 51 sculptures by artists and designers including Pam Hogg, Andrew Logan and Kitty Johnson.
The sculptures in Birmingham (David Oates/PA)
Actor Bonneville, DJ Fatboy Slim, and TV presenter and actor Ray are among the stars who will voice real-life stories and poems about the pandemic as part of the exhibition.
Actor Christopher Eccleston, actress Sarah Parish and singer KT Tunstall will also feature.
The sculptures will be auctioned off at a later date with “substantial proceeds” from the sale going to NHS Charities Together, the organisers said in a statement.