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JNCASR team develops potential drug candidate for Alzheimer s

JNCASR team develops potential drug candidate for Alzheimer’s Updated: Updated: March 06, 2021 21:36 IST The team observed that the small molecule TGR63 reduced amyloid plaques in mice brains and reversed cognitive decline Share Article AAA Brain scan: A key feature of Alzheimer’s is deposition of amyloid plaques and neurofibrillary tangles.   | Photo Credit: haydenbird The team observed that the small molecule TGR63 reduced amyloid plaques in mice brains and reversed cognitive decline Researchers from Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bengaluru, have developed a small molecule that helps disrupt and reduce formation of amyloid plaques in the brains of mice with Alzheimer’s Disease. The group is planning to take this molecule, which is a potential drug candidate, forward for clinical studies. The results of their study were published in the journal

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