our gut. e.coli, they re called entero bacteria. they re normal in your gi track. they don t cause a problem. but if they get out that your bloodstream, get into your lungs, get into your kid anies, can cause serious infections. now this happens most often in really sick patients in the icu. they will have indwelling catheters for their urine. they will have catheters in their bloodstream. they will be on respirators. when your immune system breaks down that is when the bacteria can get out. what happened over the years since 2001 they have become resistant to almost every bacteria, every antibiotic, excuse me, we have. the last big antibiotic, carbopenu used to kill everything. now they re already resistant to that. so they areed carbopenu resistant entero factor.